| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GRID1 |
| Specificity: |
This antibody reacts specifically with GRID1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GRID1 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, GluR-delta 1 (Glutamate receptor delta-1 subunit), GluR-delta 1 functions as a glutamate receptor that regulates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity, Ionotropic glutamate receptors are divided into two categories, Kainate/AMPA receptors consist of seven structurally related subunits, Localized to the cell junction and the postsynaptic cell membrane, a chronic and severe brain disorder, also known as GRID1, and are primarily responsible for fast excitatory neurotransmissions carried out by glutamate, both of which contain glutamate-gated, cation-specific ion channels, designated GluR-1 to -7, is a multi-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain, namely NMDA receptors and kainate/AMPA receptors, neural development and neurodegeneration, Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GluD1 KIAA1220 |
| Also known as: |
GRID1 Polyclonal Antibody |
| Other name: |
Anti-GRID1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GRID1 |
| Short name: |
Anti-GRID1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GRID1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4575 |
| Gene: |
GRID1 |
More about : GRID1 |
| Long gene name: |
glutamate ionotropic receptor delta type subunit 1 |
| Synonyms gene name: |
delta 1 , glutamate receptor, ionotropic |
| Locus: |
10q23, 1-q23, 2 |
| Discovery year: |
1997-10-21 |
| GenBank acession: |
AB033046 |
| Entrez gene record: |
2894 |
| RefSeq identity: |
XM_043613 |
| Classification: |
Glutamate ionotropic receptor delta type subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000018650 |