| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Glycine Receptor alpha 1 + alpha 2 |
| Specificity: |
This antibody reacts specifically with Glycine Receptor alpha 1 + alpha 2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Glycine Receptor alpha 1 + alpha 2 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation, Each subunit consists of a large extracellular N-terminal region, Four genes encoding glycine receptor alpha subunits have been identified, The receptors are pentameric membrane proteins which form chloride channels, and a large cytoplasmic domain, four transmembrane domains, together with a single beta polypeptide, which mediate fast inhibitory neurotransmission, Glycine receptors are members of the ligand-gated ion channel superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GLRA1, GLRA1_HUMAN, GLRA2, GLRA2_HUMAN, Glycine receptor, Glycine receptor, Glycine receptor 48 kDa subunit, Glycine receptor alpha 1, Glycine receptor alpha 2, Glycine receptor subunit alpha 1, Glycine receptor subunit alpha 2, STHE, alpha 1 subunit, alpha 2 subunit, GLRA1+GLRA2 |
| Also known as: |
Glycine Receptor alpha 1 + alpha 2 Antibody |
| Other name: |
Anti-Glycine Receptor alpha 1 + alpha 2 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Glycine Receptor alpha 1 + alpha 2 |
| Short name: |
Fluor 594, Anti-Glycine Receptor alpha 1 + alpha 2 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Glycine Receptor a 1 and a 2 |