| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
5HT7 Receptor/SR-7 |
| Specificity: |
This antibody reacts specifically with 5HT7 Receptor/SR-7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In platelets and gut, In the CNS, SR-3 is a ligand-gated ion channel, SR-4 mediates widespread effects in central and peripheral nervous systems, SR-7 belongs to the superfamily of G protein-coupled receptors, Serotonin mediates its effects through several of G protein coupled receptors, The gene which encodes SR-7 maps to human chromosome 10q21-q24, a hormone and a mitogen, and it is predominantly expressed in the gut, appetite, behavior and drug abuse, designated 5-HT receptors or alternatively SR receptors, including anxiety, platelets and central nervous system (CNS), respectively, serotonin modulates several processes, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, sleep, whereas all other known serotonin receptor subtypes are G protein-coupled receptors, Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
5 HT X, 5 hydroxytryptamine receptor 7, 5 hydroxytryptamine serotonin receptor 7, 5 hydroxytryptamine serotonin receptor 7 adenylate cyclase coupled, 5-HT-7, 5-HT-X, 5-HT7, 5-hydroxytryptamine receptor 7, 5HT7, 5HT7R_HUMAN, HTR7, Serotonin 5 HT 7 receptor, Serotonin receptor 7, HT 7 |
| Also known as: |
5HT7 Receptor/SR-7 Polyclonal Antibody |
| Other name: |
Anti-5HT7 Receptor/SR-7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
5HT7 Receptor/SR-7 |
| Short name: |
Anti-5HT7 Receptor/SR-7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-5HT7 Receptor/SR-7 (polyclonal) |
| Alternative technique: |
polyclonals |