| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
5HT3D + 5HT3E Receptor |
| Specificity: |
This antibody reacts specifically with 5HT3D + 5HT3E Receptor |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human 5HT3D + 5HT3E Receptor |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
5-HT3 (5-hydroxytryptamine-3) receptor is the only ligand-gated ion channel within the family of serotonin receptors, Expression of HTR3D is restricted to kidney, HTR3C, HTR3D (5-hydroxytryptamine receptor 3D), HTR3D and HTR3E, HTR3D is localized within the endoplasmic reticulum, HTR3D must be co-expressed with SR-3A to form a functional 5-HT3 receptor complex on the plasma membrane, It is composed of five subunits consisting of SR-3A, SR-3B, There are three different isoforms of HTR3D that are expressed as a result of alternative splicing events, Until it is complexed with SR-3A, also known as Serotonin receptor 3D, colon and liver, is a 454 amino acid multi-pass membrane protein that is one components of the pentaheteromeric complex that forms the 5-HT3 receptor, sexuality and appetite, sleep, vomiting, Serotonin is a monoamine neurotransmitter that is made in serotonergic neurons in the CNS (central nervous system) and is important in the regulation of mood |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
5 HT3 E, 5 HT3D, 5 HT3E, 5 HT3c1, 5 hydroxytryptamine receptor 3 subunit D, 5 hydroxytryptamine receptor 3 subunit E, 5 hydroxytryptamine receptor 3D, 5 hydroxytryptamine receptor 3E, 5 hydroxytryptamine serotonin receptor 3 family member D, 5 hydroxytryptamine serotonin receptor 3 family member E, 5HT3D, 5HT3D_HUMAN, 5HT3E_HUMAN, HTR3D, HTR3E, MGC119636, MGC119637, MGC120035, MGC120036, MGC120037, Serotonin 5 HT 3D receptor, Serotonin receptor 3D, Serotonin receptor 3E, 5 HT3 D |
| Also known as: |
5HT3D + 5HT3E Receptor Antibody |
| Other name: |
Anti-5HT3D + 5HT3E Receptor |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
5HT3D + 5HT3E Receptor |
| Short name: |
Fluor 594, Anti-5HT3D + 5HT3E Receptor |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-5HT3D and 5HT3E Receptor |