| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PPP2R5C |
| Specificity: |
This antibody reacts specifically with PPP2R5C |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PPP2R5C |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
-B56-Beta, -B56-gamma and -B56-Delta, A group of proteins that are intimately involved in this process are the protein phosphatases, An additional protein phosphatase catalytic subunit, Four major families of protein phosphatase catalytic subunits have been identified, In general, PP2A, PP2A-B-Alpha and -B-Beta, PP2A-B56-Alpha, PP2A-C-Alpha and -C-Beta, PP2B (calcineurin) and PP2C, PPX (also known as PP4) is a putative member of a novel PP family, Regulatory subunits include PP2A-A-Alpha and -A-Beta, The PP2A catalytic subunit associates with a variety of regulatory subunits, The PP2A family comprises subfamily members PP2A Alpha and PP2A Beta, a variable subunit, and a catalytic subunit, designated PP1, homeostasis and apoptosis, including division, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, In eukaryotes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
B56G PR61G |
| Also known as: |
PPP2R5C Polyclonal Antibody |
| Other name: |
Anti-PPP2R5C Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PPP2R5C |
| Short name: |
Anti-PPP2R5C (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, g (polyclonal), regulatory functionnal sequence B', antibody to-protein phosphatase 2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
B56G and PR61G, PPP2R5C and IDBG-20535 and ENSG00000078304 and 5527, PPP2R5C and IDBG-634666 and ENSBTAG00000020192 and 505757, Ppp2r5c and IDBG-171384 and ENSMUSG00000017843 and 26931, centromeric region and cellular component this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006508 and proteolysis and biological process this GO :0006977 and DNA damage response, gamma, nuclei, protein phosphatase type 2A regulator activity, regulatory subunit B', signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007165 and signal transduction and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008601 and protein phosphatase type 2A regulator activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016485 and protein processing and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0050790 and regulation of catalytic activity and biological process, this GO :0000159 and protein phosphatase type 2A complex and cellular component this GO :0000775 and chromosome, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity and also this GO :0008601 : protein phosphatase type 2A regulator activity, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, this GO :0008601 : protein phosphatase type 2A regulator activity, protein phosphatase 2 |
| Identity: |
9311 |
| Gene: |
PPP2R5C |
More about : PPP2R5C |
| Long gene name: |
protein phosphatase 2 regulatory subunit B', gamma |
| Synonyms gene name: |
gamma isoform , protein phosphatase 2, regulatory subunit B (B56) |
| Locus: |
14q32, 31 |
| Discovery year: |
1996-05-08 |
| GenBank acession: |
L42375 |
| Entrez gene record: |
5527 |
| Pubmed identfication: |
7592815 |
| RefSeq identity: |
NM_002719 |
| Classification: |
Protein phosphatase 2 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000171597 |