| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Serine/threonine-protein kinase MAK-V |
| Specificity: |
This antibody reacts specifically with Serine/threonine-protein kinase MAK-V |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Serine/threonine-protein kinase MAK-V |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-Î, Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome, also designated MAK-V in mouse, and CAB39, and may provide diagnostic-prognostic value as a molecular marker, has been identified as a novel SNF1-related serine/threonine kinase, which may modulate the efficiency of insulin signal transduction, ±, The HUNK (hormonally upregulated Neu-associated kinase) protein |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HUNK, HUNK_HUMAN, Hormonally up-regulated neu tumor-associated kinase, Hormonally upregulated neu associated, Hormonally upregulated neu associated kinase, Hormonally upregulated neu tumor associated kinase, MAKV, Serine/threonine-protein kinase MAK-V, B19 |
| Also known as: |
Serine/threonine-protein kinase MAK-V Antibody |
| Other name: |
Anti-Serine/threonine-protein kinase MAK-V |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Serine/threonine-protein kinase MAK-V |
| Short name: |
Fluor 594, Anti-Serine/threonine-protein kinase MAK-V |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Serine/threonine-protein phosphorylation catalyst MAK-V |