| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RAMP3 |
| Specificity: |
This antibody reacts specifically with RAMP3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RAMP3 |
| Gene ID: |
10268 |
| Swiss Prot: |
O60896 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as a receptor for adrenomedullin (AM) together with CALCRL, Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane, Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
RAMP3 Polyclonal Antibody |
| Other name: |
Anti-RAMP3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RAMP3 |
| Short name: |
Anti-RAMP3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-receptor (G protein-coupled) activity modifying protein 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cell surfaces, DNA-templated and biological process this GO :0071392 and cellular response to estradiol stimulus and biological process this GO :0072659 and protein localization to plasma membrane and biological process this GO :0086103 and G-protein coupled receptor signaling pathway involved in heart process and biological process this GO :0090004 and positive regulation of establishment of protein localization to plasma membrane and biological process, RAMP3 and IDBG-15634 and ENSG00000122679 and 10268, RAMP3 and IDBG-634040 and ENSBTAG00000020704 and 613547, Ramp3 and IDBG-148614 and ENSMUSG00000041046 and 56089, coreceptor activity, this GO :0001921 and positive regulation of receptor recycling and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005764 and lysosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006816 and calcium ion transport and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0008565 and protein transporter activity and molecular function this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0015031 and protein transport and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0031623 and receptor internalization and biological process this GO :0043235 and receptor complex and cellular component this GO :0045892 and negative regulation of transcription, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0008565 : protein transporter activity and also this GO :0015026 : coreceptor activity, this GO :0005515 : protein binding, this GO :0008565 : protein transporter activity, this GO :0015026 : coreceptor activity, receptor (G protein-coupled) activity modifying protein 3 |
| Identity: |
9845 |
| Gene: |
RAMP3 |
More about : RAMP3 |
| Long gene name: |
receptor activity modifying protein 3 |
| Synonyms gene name: |
receptor activity modifying protein 3 receptor (calcitonin) activity modifying protein 3 receptor (G protein-coupled) activity modifying protein 3 |
| Locus: |
7p13 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AJ001016 |
| Entrez gene record: |
10268 |
| RefSeq identity: |
NM_005856 |
| Classification: |
Receptor (G protein-coupled) activity modifying proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000023729 |