| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
POMC |
| Specificity: |
This antibody reacts specifically with POMC |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human POMC |
| Gene ID: |
5443 |
| Swiss Prot: |
P01189 |
| Applications: |
IF(IHC-F), IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Beta-endorphin and Met-enkephalin are endogenous opiates, MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes, ACTH stimulates the adrenal glands to release cortisol |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MSH POC CLIP ACTH NPP LPH |
| Also known as: |
POMC Polyclonal Antibody |
| Other name: |
Anti-POMC Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
POMC |
| Short name: |
Anti-POMC (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-proopiomelanocortin (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ACTH and CLIP and LPH and MSH and NPP and POC, Extracellular, POMC and IDBG-34380 and ENSG00000115138 and 5443, POMC and IDBG-637211 and ENSBTAG00000007897 and 281416, Pomc and IDBG-127850 and ENSMUSG00000020660 and 18976, this GO :0001664 and G-protein coupled receptor binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0006091 and generation of precursor metabolites and energy and biological process this GO :0007165 and signal transduction and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0016486 and peptide hormone processing and biological process this GO :0030141 and secretory granule and cellular component this GO :0031781 and type 3 melanocortin receptor binding and molecular function this GO :0031782 and type 4 melanocortin receptor binding and molecular function this GO :0032098 and regulation of appetite and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0033059 and cellular pigmentation and biological process this GO :0034774 and secretory granule lumen and cellular component this GO :0042593 and glucose homeostasis and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0070873 and regulation of glycogen metabolic process and biological process this GO :0070996 and type 1 melanocortin receptor binding and molecular function this GO :2000852 and regulation of corticosterone secretion and biological process, this GO :0001664 : G-protein coupled receptor binding, this GO :0001664 : G-protein coupled receptor binding and also this GO :0005102 : receptor binding and also this GO :0005179 : hormone activity and also this GO :0031781 : type 3 melanocortin receptor binding and also this GO :0031782 : type 4 melanocortin receptor binding and also this GO :0070996 : type 1 melanocortin receptor binding, this GO :0005102 : receptor binding, this GO :0005179 : hormone activity, this GO :0031781 : type 3 melanocortin receptor binding, this GO :0031782 : type 4 melanocortin receptor binding, this GO :0070996 : type 1 melanocortin receptor binding, type 1 melanocortin receptor binding, proopiomelanocortin |
| Identity: |
9201 |
| Gene: |
POMC |
More about : POMC |
| Long gene name: |
proopiomelanocortin |
| Synonyms name: |
adrenocorticotropin beta-lipotropin alpha-melanocyte stimulating hormone beta-melanocyte stimulating hormone beta-endorphin adrenocorticotropic hormone opiomelanocortin prepropeptide |
| Locus: |
2p23, 3 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
5443 |
| Pubmed identfication: |
6254047 9620771 |
| RefSeq identity: |
NM_001035256 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000094764 |