| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SLITRK4 |
| Specificity: |
This antibody reacts specifically with SLITRK4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SLITRK4 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A study using genome-wide transcriptional profiling suggested that the gene encoding SLITRK4, As compared with its family member SLITRK2, CA3 region of the hippocampus and cortical plate, SLITRK4 (SLIT and NTRK-like protein 4) is a 837 amino acid single-pass type I membrane protein that contains 18 LRR (leucine-rich) repeats and is expressed in neural tissues, SLITRK4 may be upregulated in some astrocytic brain tumors such as glioblastomas, SLITRK4 only weakly suppresses neurite outgrowth, as well as the ARL5B and PLA2G7 genes, astrocytomas and primitive neuroectodermal tumors, hypothalamus, may be involved in the pathogenesis of preeclampsia, specifically in the thalamus, subventricular zone, SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DKFZp547M2010 |
| Also known as: |
SLITRK4 Polyclonal Antibody |
| Other name: |
Anti-SLITRK4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SLITRK4 |
| Short name: |
Anti-SLITRK4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SLITRK4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23502 |
| Gene: |
SLITRK4 |
More about : SLITRK4 |
| Long gene name: |
SLIT and NTRK like family member 4 |
| Synonyms gene name: |
SLIT and NTRK-like family, member 4 |
| Locus: |
Xq27, 3 |
| Discovery year: |
2004-01-08 |
| GenBank acession: |
BC040986 |
| Entrez gene record: |
139065 |
| Pubmed identfication: |
14557068 |
| RefSeq identity: |
NM_173078 |
| Havana BLAST/BLAT: |
OTTHUMG00000022580 |
| Locus Specific Databases: |
Mental Retardation database |