| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NOD2 |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB |
| Recommended dilutions: |
1-0, 3ug/ml, ELISA (peptide) LOD: 1:64000, Western blot: 0 |
| Notes: |
Optimal dilution of the NOD2 antibody should be determined by the researcher |
| Intented use: |
This NOD2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
64127 |
| Purity: |
Antigen affinity |
| Description: |
CARD15, caspase recruitment domain family, member 15, Additional name(s) for this target protein: Nucleotide-binding oligomerization domain-containing protein 2 |
| Immunogen: |
Amino acids KFRFTDRERHCSPTD were used as the immunogen for this NOD2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the NOD2 antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NOD2 |
| Short name: |
NOD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
nucleotide-binding oli this GO merization domain containing 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARD domain binding, Cell surfaces, NOD2 and IDBG-30654 and ENSG00000167207 and 64127, NOD2 and IDBG-631640 and ENSBTAG00000020936 and 444867, Nod2 and IDBG-179050 and ENSMUSG00000055994 and 257632, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046645 and positive regulation of gamma-delta T cell activation and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0050871 and positive regulation of B cell activation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0060585 and positive regulation of prostaglandin-endoperoxide synthase activity and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070431 and nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0071224 and cellular response to peptidoglycan and biological process this GO :0071225 and cellular response to muramyl dipeptide and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071608 and macrophage inflammatory protein-1 alpha production and biological process this GO :0090022 and regulation of neutrophil chemotaxis and biological process this GO :2000110 and negative regulation of macrophage apoptotic process and biological process this GO :2000363 and positive regulation of prostaglandin-E synthase activity and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002227 and innate immune response in mucosa and biological process this GO :0002253 and activation of immune response and biological process this GO :0002367 and cytokine production involved in immune response and biological process this GO :0002381 and immunoglobulin production involved in immunoglobulin mediated immune response and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0002710 and negative regulation of T cell mediated immunity and biological process this GO :0002732 and positive regulation of dendritic cell cytokine production and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002830 and positive regulation of type 2 immune response and biological process this GO :0002862 and negative regulation of inflammatory response to antigenic stimulus and biological process this GO :0002925 and positive regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006963 and positive regulation of antibacterial peptide biosynthetic process and biological process this GO :0006965 and positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria and biological process this GO :0007254 and JNK cascade and biological process this GO :0007584 and response to nutrient and biological process this GO :0008180 and COP9 signalosome and cellular component this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009595 and detection of biotic stimulus and biological process this GO :0009986 and cell surface and cellular component this GO :0016045 and detection of bacterium and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030277 and maintenance of gastrointestinal epithelium and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031982 and vesicle and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032498 and detection of muramyl dipeptide and biological process this GO :0032500 and muramyl dipeptide binding and molecular function this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032701 and negative regulation of interleukin-18 production and biological process this GO :0032703 and negative regulation of interleukin-2 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032874 and positive regulation of stress-activated MAPK cascade and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034136 and negative regulation of toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035419 and activation of MAPK activity involved in innate immune response and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0032500 : muramyl dipeptide binding and also this GO :0042834 : peptidoglycan binding and also this GO :0050700 : CARD domain binding, this GO :0005524 : ATP binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0032500 : muramyl dipeptide binding, this GO :0042834 : peptidoglycan binding, this GO :0050700 : CARD domain binding, nucleotide-binding oli this GO merization domain containing 2 |
| Identity: |
5331 |
| Gene: |
NOD2 |
More about : NOD2 |
| Long gene name: |
nucleotide binding oligomerization domain containing 2 |
| Synonyms gene: |
IBD1 CARD15 |
| Synonyms gene name: |
caspase recruitment domain family, member 15 |
| Synonyms: |
BLAU CD PSORAS1 CLR16, 3 NLRC2 |
| Synonyms name: |
CARD domain containing 2 , leucine rich repeat and CARD domain containing 2 NOD-like receptor C2 NLR family, nucleotide-binding oligomerization domain |
| Locus: |
16q12, 1 |
| Discovery year: |
1998-07-10 |
| GenBank acession: |
AF178930 |
| Entrez gene record: |
64127 |
| Pubmed identfication: |
7809109 8587604 |
| RefSeq identity: |
NM_022162 |
| Classification: |
Caspase recruitment domain containing NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000133171 |
| Locus Specific Databases: |
LRG_177 |