| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SATB2 |
| Specificity: |
This antibody reacts specifically with SATB2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SATB2 |
| Gene ID: |
23314 |
| Swiss Prot: |
Q9UPW6 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers, Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation, May play an important role in palate formation, Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex, Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, Thought to recognize the sugar-phosphate structure of double-stranded DNA, Transcription factor controlling nuclear gene expression, at nuclear matrix- or scaffold-associated regions, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling, probably by modulating BCL11B expression, Binds to DNA |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1034 FLJ21474 |
| Also known as: |
SATB2 Polyclonal Antibody |
| Other name: |
Anti-SATB2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SATB2 |
| Short name: |
Anti-SATB2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SATB2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
21637 |
| Gene: |
SATB2 |
More about : SATB2 |
| Long gene name: |
SATB homeobox 2 |
| Synonyms gene name: |
SATB family member 2 |
| Locus: |
2q33, 1 |
| Discovery year: |
2003-07-08 |
| GenBank acession: |
AB028957 |
| Entrez gene record: |
23314 |
| RefSeq identity: |
NM_015265 |
| Classification: |
CUT class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000132767 |