| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NPDC1 |
| Specificity: |
This antibody reacts specifically with NPDC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NPDC1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
D-type cyclins, NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, NPDC-1 interacts with Cdk2, NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane, One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors, The amino acid sequence of NPDC-1 is highly conserved between mouse, This interaction can lead to an increased replication time, and Rab3 GEP (Rab3 GTP/GDP exchange protein), and human, and might have implications in final neural differentiation and apoptosis, and the transcription factor E2F1, rat, synaptobrevin 2, NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DKFZp586J0523 CAB- CAB1 |
| Also known as: |
NPDC1 Polyclonal Antibody |
| Other name: |
Anti-NPDC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NPDC1 |
| Short name: |
Anti-NPDC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NPDC1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7899 |
| Gene: |
NPDC1 |
More about : NPDC1 |
| Long gene name: |
differentiation and control 1 , neural proliferation |
| Locus: |
9q34, 3 |
| Discovery year: |
2000-08-11 |
| GenBank acession: |
AF285836 |
| Entrez gene record: |
56654 |
| Pubmed identfication: |
11245976 |
| RefSeq identity: |
NM_015392 |
| Havana BLAST/BLAT: |
OTTHUMG00000020956 |