| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ACACA |
| Specificity: |
This antibody reacts specifically with ACACA |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ACACA |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
(ACC2) may control mitochondrial fatty acid oxidation, ACC alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle, The catalytic core of ACCâ, The catalytic function of ACC alpha is regulated by phosphorylation (inactive) and dephosphorylation (active) of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA, The gene encoding ACC alpha maps to human chromosome 17 and encodes a form of ACC, These two isoforms of ACC control the amount of fatty acids in the cells, and ACCâ, except for an additional peptide of about 150 amino acids at the N-terminus, is homologous to that of the ACC&, the rate-limiting step in fatty acid synthesis, which is the major ACC in lipogenic tissues, which serve as the enzymeâ, &circ, &circ, &euro, «, «, &trade, Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, aring, s short-term regulatory mechanism |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ACC1 |
| Also known as: |
ACACA Polyclonal Antibody |
| Other name: |
Anti-ACACA Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ACACA |
| Short name: |
Anti-ACACA (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ACACA (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
84 |
| Gene: |
ACACA |
More about : ACACA |
| Long gene name: |
acetyl-CoA carboxylase alpha |
| Synonyms gene: |
ACAC ACC |
| Synonyms gene name: |
acetyl-Coenzyme A carboxylase alpha |
| Synonyms name: |
acetyl-CoA carboxylase 1 |
| Locus: |
17q12 |
| Discovery year: |
1989-09-11 |
| GenBank acession: |
U19822 |
| Entrez gene record: |
31 |
| RefSeq identity: |
NM_198836 |
| Havana BLAST/BLAT: |
OTTHUMG00000188463 |