| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ECE1 |
| Specificity: |
This antibody reacts specifically with ECE1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ECE1 |
| Gene ID: |
1889 |
| Swiss Prot: |
P42892 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Converts big endothelin-1 to endothelin-1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ECE1 Polyclonal Antibody |
| Other name: |
Anti-ECE1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ECE1 |
| Short name: |
Anti-ECE1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-endothelin converting enzyme 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cell surfaces, ECE, ECE1 and IDBG-645619 and ENSBTAG00000002977 and 281133, ECE1 and IDBG-93094 and ENSG00000117298 and 1889, Ece1 and IDBG-199213 and ENSMUSG00000057530 and 230857, metal ion binding, this GO :0001921 and positive regulation of receptor recycling and biological process this GO :0003100 and regulation of systemic arterial blood pressure by endothelin and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005765 and lysosomal membrane and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007507 and heart development and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010814 and substance P catabolic process and biological process this GO :0010815 and bradykinin catabolic process and biological process this GO :0010816 and calcitonin catabolic process and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016485 and protein processing and biological process this GO :0016486 and peptide hormone processing and biological process this GO :0017046 and peptide hormone binding and molecular function this GO :0019229 and regulation of vasoconstriction and biological process this GO :0031302 and intrinsic to endosome membrane and cellular component this GO :0031982 and vesicle and cellular component this GO :0033093 and Weibel-Palade body and cellular component this GO :0034959 and endothelin maturation and biological process this GO :0042447 and hormone catabolic process and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043583 and ear development and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0060037 and pharyngeal system development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004222 : metalloendopeptidase activity and also this GO :0017046 : peptide hormone binding and also this GO :0042803 : protein homodimerization activity and also this GO :0046872 : metal ion binding, this GO :0004222 : metalloendopeptidase activity, this GO :0017046 : peptide hormone binding, this GO :0042803 : protein homodimerization activity, this GO :0046872 : metal ion binding, endothelin converting enzyme 1 |
| Identity: |
3146 |
| Gene: |
ECE1 |
More about : ECE1 |
| Long gene name: |
endothelin converting enzyme 1 |
| Synonyms gene: |
ECE |
| Locus: |
1p36, 12 |
| Discovery year: |
1995-12-08 |
| GenBank acession: |
D49471 |
| Entrez gene record: |
1889 |
| Pubmed identfication: |
7805846 7864876 17592116 |
| RefSeq identity: |
NM_001397 |
| Havana BLAST/BLAT: |
OTTHUMG00000002625 |