| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NME4/nm23-H4 |
| Specificity: |
This antibody reacts specifically with NME4/nm23-H4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NME4/nm23-H4 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Based on sequence analysis, Low amounts of nm23-H4 are observed in the brain and in blood leukocytes, NDP kinases A and B are identical to two isotypes of human nm23 homologs, a potential suppressor of metastasis, a transcription factor that binds to nuclease-hypersensitive elements at positions 142 to 115 of the human c-Myc promoter, also designated nucleoside diphosphate kinase A (NDK A) or Tumor metastatic process-associated protein, and skeletal muscle tissues, appears to be highly related to nucleotide diphosphate kinases (NDP), heart, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential, liver, nm23, nm23-H1 and nm23-H2, nm23-H2 is also identical in sequence to PuF, nm23-H3 and nm23-H4 are important for the synthesis of nucleoside triphosphates and may play a role in apoptosis induction and hematopoiesis, nm23-H4 localizes to the mitochondrial intermembrane space and is widely expressed, respectively, small intestine, with higher levels detected in prostate, The nm23 gene (Metastasis inhibition factor nm23) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
nm23-H4 NM23H4 NDPKD |
| Also known as: |
NME4/nm23-H4 Polyclonal Antibody |
| Other name: |
Anti-NME4/nm23-H4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NME4/nm23-H4 |
| Short name: |
Anti-NME4/nm23-H4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NME4/nm23-H4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7852 |
| Gene: |
NME4 |
More about : NME4 |
| Long gene name: |
NME/NM23 nucleoside diphosphate kinase 4 |
| Synonyms gene name: |
non-metastatic cells 4, protein expressed in |
| Locus: |
16p13, 3 |
| Discovery year: |
1996-12-19 |
| GenBank acession: |
Y07604 |
| Entrez gene record: |
4833 |
| Pubmed identfication: |
9099850 19852809 |
| RefSeq identity: |
NM_005009 |
| Classification: |
NME/NM23 family |
| Havana BLAST/BLAT: |
OTTHUMG00000047995 |