| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LGI3 |
| Specificity: |
This antibody reacts specifically with LGI3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LGI3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
All LRR repeats contain a variable segment and a highly conserved segment, LGI3 contains five LRR repeats and seven EAR repeats, LGI3 has been shown to colocalize with endocytosis-associated proteins, Leucine-rich glioma-inactivated protein 3 (LGI3), The gene encoding LGI3 maps to chromosome 8p21, Widely expressed, allowing it to accommodate several leucine residues within a tightly packed core, also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, and Syntaxin, horseshoe fold, is a 548 amino acid secretory protein, lipid raft markers, the latter of which accounts for 11 or 12 residues of the entire LRR motif, with highest levels in brain and lung, &circ, «, /â, 3, The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic &, aring |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
LGI3 Polyclonal Antibody |
| Other name: |
Anti-LGI3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LGI3 |
| Short name: |
Anti-LGI3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 3 (polyclonal), antibody to-leucine-rich repeat LGI family |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, LGI3 and IDBG-10343 and ENSG00000168481 and 203190, LGI3 and IDBG-634665 and ENSBTAG00000004578 and 516661, Lgi3 and IDBG-178840 and ENSMUSG00000033595 and 213469, member 3, protein binding, this GO :0003824 and catalytic activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0006887 and exocytosis and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008152 and metabolic process and biological process this GO :0017157 and regulation of exocytosis and biological process this GO :0030054 and cell junction and cellular component this GO :0043005 and neuron projection and cellular component, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, leucine-rich repeat LGI family |
| Identity: |
18711 |
| Gene: |
LGI3 |
More about : LGI3 |
| Long gene name: |
leucine rich repeat LGI family member 3 |
| Synonyms gene name: |
leucine-rich repeat LGI family, member 3 |
| Locus: |
8p21, 3 |
| Discovery year: |
2002-05-30 |
| GenBank acession: |
AJ487518 |
| Entrez gene record: |
203190 |
| Pubmed identfication: |
12023020 18628660 |
| Havana BLAST/BLAT: |
OTTHUMG00000131599 |