| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LPPR4 |
| Specificity: |
This antibody reacts specifically with LPPR4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LPPR4 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Exclusively expressed in neurons, LPPR4 (lipid phosphate phosphatase-related protein type 4), LPPR4 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 1p21, LPPR4 hydrolyzes lysophosphatidic acid (LPA) and facilitates axonal outgrowth during development and regenerative sprouting, PAP-2 proteins function independently of Mg2+ and are insensitive to NEM (N-ethylmaleimide) inhibition, PHP1, PRG1 or PRG-1, The lipid phosphates degraded by this family include ceramide 1-phosphate (C1P), also known as LPR4, is a 763 amino acid multi-pass membrane protein that belongs to the PA-phosphatase related phosphoesterase family, phosphatidic acid (PA) and lysophosphatidic acid (LPA), sphingosine 1-phosphate (S1P), 2, Phosphatidate phosphatases are a family of integral membrane glycoproteins that dephosphorylate a variety of lipid phosphates and play a role in signal transduction via the phospholipase D pathway |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PRG-1 LPPR4 KIAA0455 PHP1 |
| Also known as: |
LPPR4 Polyclonal Antibody |
| Other name: |
Anti-LPPR4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LPPR4 |
| Short name: |
Anti-LPPR4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-LPPR4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23496 |
| Gene: |
PLPPR4 |
More about : PLPPR4 |
| Long gene name: |
phospholipid phosphatase related 4 |
| Synonyms name: |
plasticity related gene-1 |
| Locus: |
1p21, 2 , 3-p21 |
| Discovery year: |
2015-10-14 |
| GenBank acession: |
AF541281 AB007924 |
| Entrez gene record: |
9890 |
| Pubmed identfication: |
12730698 |
| RefSeq identity: |
NM_014839 |
| Classification: |
Phospholipid phosphatase related |
| Havana BLAST/BLAT: |
OTTHUMG00000010763 |