| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
IL1RAPL2/IL-1R9 |
| Specificity: |
This antibody reacts specifically with IL1RAPL2/IL-1R9 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human IL1RAPL2/IL-1R9 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
IL-1R9 and IL-1R8 do not activate NF-kB, IL-1R9 is highly homologous to IL-1R8 and the IL-1 accessory protein receptor chains, It is a single pass transmembrane protein with a highly conserved cytoplasmic region that is slightly longer than that of other family members, The genes encoding IL-1R9 and IL-1R8 are both found on the X-chromosome in the region associated with X-linked non-syndromic mental retardation, Unlike other family members, IL-1R9 is a member of the interleukin-1/Toll-like receptor family expressed in fetal brain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
IL-1R9 TIGIRR-1 IL1RAPL-2 IL1R9 |
| Also known as: |
IL1RAPL2/IL-1R9 Polyclonal Antibody |
| Other name: |
Anti-IL1RAPL2/IL-1R9 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
IL1RAPL2/IL-1R9 |
| Short name: |
Anti-IL1RAPL2/IL-1R9 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-interleukin 1 receptor accessory protein-like 2/Interleukin-1R9 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
IL1RAPL2 and IDBG-633230 and ENSBTAG00000044025 and 523444, IL1RAPL2 and IDBG-80984 and ENSG00000189108 and 26280, Il1rapl2 and IDBG-173736 and ENSMUSG00000059203 and 60367, Plasma membranes, Type II, Type II, Type II, blocking receptor activity, blocking receptor activity and also this GO :0005515 : protein binding, blocking receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0007165 and signal transduction and biological process this GO :0007417 and central nervous system development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process, interleukin-1, this GO :0004908 and interleukin-1 receptor activity and molecular function this GO :0004910 and interleukin-1, this GO :0004908 : interleukin-1 receptor activity, this GO :0004908 : interleukin-1 receptor activity and also this GO :0004910 : interleukin-1, this GO :0004910 : interleukin-1, this GO :0005515 : protein binding, interleukin 1 receptor accessory protein-like 2 |
| Identity: |
5997 |
| Gene: |
IL1RAPL2 |
More about : IL1RAPL2 |
| Long gene name: |
interleukin 1 receptor accessory protein like 2 |
| Locus: |
Xq22, 3 |
| Discovery year: |
1999-11-19 |
| GenBank acession: |
AF181285 |
| Entrez gene record: |
26280 |
| Pubmed identfication: |
10757639 |
| RefSeq identity: |
NM_017416 |
| Classification: |
Immunoglobulin like domain containing Interleukin receptors TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000022141 |
| Locus Specific Databases: |
Mental Retardation database |