| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HMX2 |
| Specificity: |
This antibody reacts specifically with HMX2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HMX2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
HMX2 (H6 family homeobox 2), HMX2 functions as a transcription factor that assists in specification of neuronal cell types and is essential for proper development of hypothalamus and inner ear, Hemizygous deletions of the gene encoding HMX2 are thought to lead to vestibular dysfunction, also known as H6L or Nkx5-2, inner ear malformations and congenital sensorineural hearing loss, is a 273 amino acid nuclear protein that belongs to the HMX homeobox family and contains one homeobox DNA-binding domain, thereby playing a role in transcriptional regulation and the control of gene expression, The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NKX5-2 |
| Also known as: |
HMX2 Polyclonal Antibody |
| Other name: |
Anti-HMX2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HMX2 |
| Short name: |
Anti-HMX2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HMX2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
5018 |
| Gene: |
HMX2 |
More about : HMX2 |
| Long gene name: |
H6 family homeobox 2 |
| Synonyms gene name: |
homeo box (H6 family) 2 |
| Locus: |
10q26, 13 |
| Discovery year: |
1994-12-19 |
| Entrez gene record: |
3167 |
| Pubmed identfication: |
7647458 |
| RefSeq identity: |
XM_370580 |
| Classification: |
NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000019198 |