| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Adracalin |
| Specificity: |
This antibody reacts specifically with Adracalin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Adracalin |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Aladin plays a role in peripheral and central nervous system development, Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome, It is widely expressed, RNA processing and transcription, Robust expression in neural systems associated with cognitive, These proteins have a wide variety of functions, Triple A syndrome is characterized by achalasia, adrenal gland and gastrointestinal structures, alacrima and adrenocortico-tropin-resistant adrenal insufficiency, cerebellum, corpus callosum, including signal transduction regulation, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome, with the highest expression seen in pituitary gland, Aladin (Adracalin) belongs to a family of WD repeat-containing proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Adracalin Polyclonal Antibody |
| Other name: |
Anti-Adracalin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Adracalin |
| Short name: |
Anti-Adracalin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Adracalin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13666 |
| Gene: |
AAAS |
More about : AAAS |
| Long gene name: |
aladin WD repeat nucleoporin |
| Synonyms gene name: |
achalasia, adrenocortical insufficiency, adrenocortical insufficiency, alacrimia , alacrimia (Allgrove, triple-A) achalasia |
| Synonyms name: |
aladin Allgrove, triple-A adracalin |
| Locus: |
12q13, 13 |
| Discovery year: |
2000-11-08 |
| GenBank acession: |
AJ289841 |
| Entrez gene record: |
8086 |
| Pubmed identfication: |
11062474 |
| Classification: |
Nucleoporins WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000169729 |