| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ATBF1 |
| Specificity: |
This antibody reacts specifically with ATBF1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ATBF1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ATBF1 also functions in ATPase activity (6), ATBF1 is highly expressed in spleen and brain tissues (7), ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1â, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5), ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6), Additionally, Alternative splicing generates the ATBF1-A and ATBF1-B (2, Besides functioning in transcription regulation, In the small intestine, The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4), The gene encoding human ATBF1 maps to chromosome 16q22, While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2, &euro, &ldquo, 1 (8), 3), 3), 3), 3-q23, AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ZNF927 |
| Also known as: |
ATBF1 Polyclonal Antibody |
| Other name: |
Anti-ATBF1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ATBF1 |
| Short name: |
Anti-ATBF1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ATBF1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
777 |
| Gene: |
ZFHX3 |
More about : ZFHX3 |
| Long gene name: |
zinc finger homeobox 3 |
| Synonyms gene: |
ATBF1 |
| Synonyms gene name: |
AT-binding transcription factor 1 |
| Locus: |
16q22, 2-q22, 3 |
| Discovery year: |
1994-11-02 |
| GenBank acession: |
D10250 |
| Entrez gene record: |
463 |
| Pubmed identfication: |
1719379 7592926 |
| RefSeq identity: |
NM_006885 |
| Classification: |
ZF class homeoboxes and pseudogenes Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000137599 |