| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HYPE/HIP13 |
| Specificity: |
This antibody reacts specifically with HYPE/HIP13 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HYPE |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, HYPE also contains two tetratricopeptide repeats (TPR), HYPE is thought to interact with Huntingtin, The gene that encodes HYPE is located on chromosome 12, Trisomy 12p leads to facial development defects, a protein which induces neurodegeneration when mutated, achondrogenesis and Kniest dysplasia, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy, which encodes over 1, which may be involved in protein-protein interaction, 100 genes within 132 million bases and makes up about 4, 5% of the human genome, Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HYPE HIP13 |
| Also known as: |
HYPE/HIP13 Polyclonal Antibody |
| Other name: |
Anti-HYPE/HIP13 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HYPE/HIP13 |
| Short name: |
Anti-HYPE/HIP13 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-HYPE/HIP13 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18416 |
| Gene: |
FICD |
More about : FICD |
| Long gene name: |
FIC domain containing |
| Synonyms name: |
coli) , huntingtin interacting protein 13 fic S-phase protein cell division homolog (E |
| Locus: |
12q23, 3 |
| Discovery year: |
2007-12-04 |
| GenBank acession: |
AF049611 |
| Entrez gene record: |
11153 |
| Pubmed identfication: |
9700202 |
| RefSeq identity: |
NM_007076 |
| Havana BLAST/BLAT: |
OTTHUMG00000169569 |