| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PROSAAS |
| Specificity: |
This antibody reacts specifically with PROSAAS |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from rat PROSAAS |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Expressed in pancreas and brain, In conjunction with chromosome Y, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition, The gene encoding PCSK1N maps to human chromosome X, There are a number of conditions related to an abnormal number and combination of sex chromosomes, as an X and a Y chromosome lead to normal male development, chromosome X is responsible for sex determination, color blindness, hemophilia and Duchenne muscular dystrophy, some of which include Turner's syndrome, which contains nearly 153 million base pairs and houses over 1, while two copies of an X chromosome lead to normal female development, 000 genes, PCSK1N is a 260 amino acid protein that is both secreted and localized to the trans-Golgi network |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SAAS SgVIII SCG8 proSAAS PEN BigLEN |
| Also known as: |
PROSAAS Polyclonal Antibody |
| Other name: |
Anti-PROSAAS Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PROSAAS |
| Short name: |
Anti-PROSAAS (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PROSAAS (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17301 |
| Gene: |
PCSK1N |
More about : PCSK1N |
| Long gene name: |
proprotein convertase subtilisin/kexin type 1 inhibitor |
| Locus: |
Xp11, 23 |
| Discovery year: |
2001-11-30 |
| GenBank acession: |
AF181562 |
| Entrez gene record: |
27344 |
| Pubmed identfication: |
10632593 |
| RefSeq identity: |
NM_013271 |
| Classification: |
Granins |
| Havana BLAST/BLAT: |
OTTHUMG00000034502 |