| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
THOP1/Thimet Oligopeptidase |
| Specificity: |
This antibody reacts specifically with THOP1/Thimet Oligopeptidase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Thimet Oligopeptidase |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is important in cytoplasmic peptide degradation and involved in metabolism of neuropeptides that are less than 20 amino acids in length, The gene for the protein maps against chromosome 19q13, Thimet oligopeptidase can degrade the b-Amyloid precursor protein and generate amyloidogenic fragments, Thimet oligopeptidase is highly expressed in testis but can also be detected in liver, also designated soluble metallo-endopeptidase, is a cytoplasmic protein belonging to the peptidase M3 family, lung and kidney, 3, Thimet oligopeptidase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
THOP1/Thimet Oligopeptidase Antibody |
| Other name: |
Anti-THOP1/Thimet Oligopeptidase |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
THOP1/Thimet Oligopeptidase |
| Short name: |
Fluor 594, Anti-THOP1/Thimet Oligopeptidase |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-thimet oli this GO peptidase 1/Thimet Oligopeptidase |
| Alternative to gene target: |
Cytoplasm, EP24, THOP1 and IDBG-16324 and ENSG00000172009 and 7064, THOP1 and IDBG-644496 and ENSBTAG00000020446 and 510889, Thop1 and IDBG-176844 and ENSMUSG00000004929 and 50492, metal ion binding, this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006508 and proteolysis and biological process this GO :0006518 and peptide metabolic process and biological process this GO :0008233 and peptidase activity and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0042277 and peptide binding and molecular function this GO :0046872 and metal ion binding and molecular function, this GO :0004222 : metalloendopeptidase activity, this GO :0004222 : metalloendopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity and also this GO :0042277 : peptide binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, this GO :0042277 : peptide binding, this GO :0046872 : metal ion binding, 15 and MEPD_HUMAN and MP78 and TOP, thimet oli this GO peptidase 1 |
| Identity: |
11793 |
| Gene: |
THOP1 |
More about : THOP1 |
| Long gene name: |
thimet oligopeptidase 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
1995-07-06 |
| Entrez gene record: |
7064 |
| Pubmed identfication: |
9790774 |
| Havana BLAST/BLAT: |
OTTHUMG00000180492 |