| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ACBP/Diazepam Binding Inhibitor |
| Specificity: |
This antibody reacts specifically with ACBP/Diazepam Binding Inhibitor |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ACBD/Diazepam Binding Inhibitor |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
8 and 16 have been identified, Jul 2008], Multipletranscript variants encoding different isoforms have been describedfor this gene, The protein is conserved fromyeast to mammals, Three pseudogeneslocated on chromosomes 6, [provided by RefSeq, a proteinthat is regulated by hormones and is involved in lipid metabolismand the displacement of beta-carbolines and benzodiazepines, in addition to its role as a mediator incorticotropin-dependent adrenal steroidogenesis, whichmodulate signal transduction at type A gamma-aminobutyric acidreceptors located in brain synapses, with the most highly conserved domain consistingof seven contiguous residues that constitute the hydrophobicbinding site for medium- and long-chain acyl-Coenzyme A esters, Diazepam binding inhibitor is also known to mediate the feedbackregulation of pancreatic secretion and the postprandial release ofcholecystokinin, This gene encodes diazepam binding inhibitor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ACBP ACBD1 |
| Also known as: |
ACBP/Diazepam Binding Inhibitor |
| Other name: |
Anti-ACBP/Diazepam Binding Inhibitor |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Gene target: |
ACBP/Diazepam Binding Inhibitor |
| Short name: |
Fluor 594, Anti-ACBP/Diazepam Binding Inhibitor |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ACBP/Diazepam Binding suppressor |
| Identity: |
2690 |
| Gene: |
DBI |
More about : DBI |
| Long gene name: |
acyl-CoA binding protein , diazepam binding inhibitor |
| Synonyms gene name: |
acyl-Coenzyme A binding protein) , diazepam binding inhibitor (GABA receptor modulator |
| Synonyms name: |
endozepine |
| Locus: |
2q14, 2 |
| Discovery year: |
1988-06-09 |
| GenBank acession: |
L76366 |
| Entrez gene record: |
1622 |
| Pubmed identfication: |
1440058 |
| RefSeq identity: |
NM_020548 |
| Havana BLAST/BLAT: |
OTTHUMG00000131403 |