| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FISH |
| Specificity: |
This antibody reacts specifically with FISH |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FISH |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1), In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1), Src kinases vary in expression but are strongly regulated in vivo, The Src family of protein tyrosine kinases act in signal transduction pathways (2-4), Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, a potential Src substrate, along with activation of Src (1), catalytic activity is repressed by interacting with the SH3 domain (5-7), is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1), Fish |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FISH KIAA0418 |
| Also known as: |
FISH Polyclonal Antibody |
| Other name: |
Anti-FISH Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FISH |
| Short name: |
Anti-FISH (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-fluorescence-emitting hybridization (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
23664 |
| Gene: |
SH3PXD2A |
More about : SH3PXD2A |
| Long gene name: |
SH3 and PX domains 2A |
| Synonyms gene: |
SH3MD1 |
| Synonyms gene name: |
SH3 multiple domains 1 |
| Synonyms name: |
five SH3 domains |
| Locus: |
10q24, 33 |
| Discovery year: |
2003-12-01 |
| GenBank acession: |
AB007878 |
| Entrez gene record: |
9644 |
| Pubmed identfication: |
9687503 |
| RefSeq identity: |
NM_014631 |
| Havana BLAST/BLAT: |
OTTHUMG00000018997 |