| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
APBB2/FE65L1 |
| Specificity: |
This antibody reacts specifically with APBB2/FE65L1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human APBB2 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binding to the intracellular domain of the â, Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, Fe65L is thought to modulate the internalization and, Fe65L is thought to play a role in the pathogenesis of Alzheimer's disease, Multiple isoforms of Fe65L exist due to alternative splicing events, The gene encoding Fe65L maps to human chromosome 4, Via its ability to control the intracellular accumulation of â, methylmalonic acidemia and polycystic kidney disease, the accessibility and function of â, therefore, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes, &circ, &circ, &circ, «, «, «, -Amyloid, -Amyloid, -Amyloid precursor protein, Fe65L is a 758 amino acid protein that contains one WW domain and two PID domains |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FE65L FE65L1 MGC35575 |
| Also known as: |
APBB2/FE65L1 Polyclonal Antibody |
| Other name: |
Anti-APBB2/FE65L1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
APBB2/FE65L1 |
| Short name: |
Anti-APBB2/FE65L1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-APBB2/FE65L1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
582 |
| Gene: |
APBB2 |
More about : APBB2 |
| Long gene name: |
amyloid beta precursor protein binding family B member 2 |
| Synonyms gene name: |
amyloid beta (A4) precursor protein-binding, family B, member 2 |
| Synonyms name: |
Fe65-like |
| Locus: |
4p14-p13 |
| Discovery year: |
1997-06-25 |
| GenBank acession: |
U62325 |
| Entrez gene record: |
323 |
| Pubmed identfication: |
8955346 9585438 |
| RefSeq identity: |
NM_173075 |
| Havana BLAST/BLAT: |
OTTHUMG00000160416 |