| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RGS21 |
| Specificity: |
This antibody reacts specifically with RGS21 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RGS21 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Gaucher disease, Human chromosome 1 spans 260 million base pairs, Parkinsonâ, RGS proteins work by functioning as GTPase-activators (which increase the GTPase activity of G protein a-subunits) thereby driving G proteins into their inactive GDP-bound form, RGS21 (regulator of G-protein signaling 21) is a 152 amino acid protein that is ubiquitously expressed and contains one RGS domain, Stickler syndrome, The gene encoding RGS21 maps to human chromosome 1q31, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, contains over 3, including those that are involved in familial adenomatous polyposis, schizophrenia and Usher syndrome, &euro, &trade, 000 genes, 2 and mouse chromosome 1 F, The regulators of G protein signaling (RGS) proteins inhibit heterotrimeric G protein signaling, s disease |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
RGS21 Polyclonal Antibody |
| Other name: |
Anti-RGS21 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RGS21 |
| Short name: |
Anti-RGS21 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RGS21 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
26839 |
| Gene: |
RGS21 |
More about : RGS21 |
| Long gene name: |
regulator of G-protein signaling 21 |
| Synonyms gene name: |
regulator of G-protein signalling 21 |
| Locus: |
1q31, 2 |
| Discovery year: |
2004-06-28 |
| GenBank acession: |
AY643711 |
| Entrez gene record: |
431704 |
| Pubmed identfication: |
15066150 |
| Classification: |
Regulators of G-protein signaling |
| Havana BLAST/BLAT: |
OTTHUMG00000035594 |