| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TAS2R7/T2R7 |
| Specificity: |
This antibody reacts specifically with TAS2R7/T2R7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TAS2R7/T2R7 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A family of G protein-coupled receptors are involved in taste perception and include T1R, Both types of taste receptors couple to various G proteins to initiate signal transduction cascades, STC 7-4 or taste receptor, Single taste receptor cells express a variety of T2Rs, T2R6 (also designatedT2R30, T2R6 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells, TRB4 or taste receptor, The activity of this receptor may stimulate Alpha-gustducin, The human homolog of T2R6, and T2R, designated T2R7 (TAS2R7, mediate PLC-Beta-2 activation and lead to the gating of TRPM5, member 130) is an integral membrane receptor protein in mice that may play a role in the perception of bitterness and in sensing the chemical composition of the gastrointestinal content, member 7) is a G protein-coupled receptor expressed in taste receptor cells of the tongue and palate epithelia, mt2r42, suggesting that each cell is capable of recognizing multiple tastants, type 2, type 2, which is involved in bitter taste perception, which is involved in sweet and umami taste perception, The sense of taste provides animals with valuable information about the quality and nutritional value of food |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
T2R7 TRB4 |
| Also known as: |
TAS2R7/T2R7 Polyclonal Antibody |
| Other name: |
Anti-TAS2R7/T2R7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TAS2R7/T2R7 |
| Short name: |
Anti-TAS2R7/T2R7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TAS2R7/T2R7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14913 |
| Gene: |
TAS2R7 |
More about : TAS2R7 |
| Long gene name: |
taste 2 receptor member 7 |
| Synonyms gene name: |
member 7 , taste receptor, type 2 |
| Locus: |
12p13, 2 |
| Discovery year: |
2001-03-21 |
| GenBank acession: |
AF227133 |
| Entrez gene record: |
50837 |
| Pubmed identfication: |
10761934 10766242 |
| Classification: |
Taste 2 receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000168505 |