| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TSK/Tsukushin/LRRC54 |
| Specificity: |
This antibody reacts specifically with Tsukushin/LRRC54 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Tsukushin/LRRC54 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
All LRR repeats contain a variable segment and a highly conserved segment, Containing nine LRR repeat and a cleavable signal peptide, Involved in extracellular secretion and intracellular transport, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, LRRC54 (leucine-rich repeat-containing protein 54), LRRC54 can be induced by 17-beta-estradiol, Niemann-Pick disease, TSKU or E2-induced gene 4 protein (E2IG4), allowing it to accommodate several leucine residues within a tightly packed core, also known as tsukushin, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11, horseshoe fold, is a 353 amino acid secreted protein that likely localizes to the cell membrane and extracellular compartments, the gene encoding LRRC54 maps to human chromosome 11, the latter of which accounts for 11 or 12 residues of the entire LRR motif, which houses over 1, &circ, «, /â, 400 genes and comprises nearly 4% of the human genome, The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
E2IG4 TSK |
| Also known as: |
Tsukushin/LRRC54 Antibody |
| Other name: |
Anti-Tsukushin/LRRC54 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Tsukushin/LRRC54 |
| Short name: |
Fluor 594, Anti-Tsukushin/LRRC54 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Tsukushin/LRRC54 |
| Identity: |
28850 |
| Gene: |
TSKU |
More about : TSKU |
| Long gene name: |
small leucine rich proteoglycan , tsukushi |
| Synonyms gene: |
LRRC54 |
| Synonyms gene name: |
leucine rich repeat containing 54 tsukushin tsukushi small leucine rich proteoglycan homolog (Xenopus laevis) |
| Locus: |
11q13, 5 |
| Discovery year: |
2005-09-13 |
| GenBank acession: |
AK075476 |
| Entrez gene record: |
25987 |
| Pubmed identfication: |
11085516 19710929 22880013 |
| RefSeq identity: |
NM_015516 |
| Havana BLAST/BLAT: |
OTTHUMG00000165238 |