| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ICA12/SOX13 |
| Specificity: |
This antibody reacts specifically with ICA12/SOX13 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ICA12 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
30 Sox genes have been identified, At present, Members of this family have been shown to be conserved during evolution and to play key roles during animal development, Some are involved in human diseases, Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes, The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages, These genes similarly contain sequences that encode for the HMG-box domain, including sex reversal, which is responsible for the sequence-specific DNA-binding activity, Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Sox-13 ICA12 MGC117216 |
| Also known as: |
ICA12/SOX13 Polyclonal Antibody |
| Other name: |
Anti-ICA12/SOX13 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ICA12/SOX13 |
| Short name: |
Anti-ICA12/SOX13 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ICA12/SOX13 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11192 |
| Gene: |
SOX13 |
More about : SOX13 |
| Long gene name: |
SRY-box 13 |
| Synonyms gene name: |
SRY (sex determining region Y)-box 13 SRY box 13 |
| Synonyms name: |
islet cell antibody 12 SRY-related HMG-box gene 13 type 1 diabetes autoantigen SRY-box 13 |
| Locus: |
1q32, 1 |
| Discovery year: |
1998-12-11 |
| Entrez gene record: |
9580 |
| Pubmed identfication: |
10198172 |
| RefSeq identity: |
NM_005686 |
| Classification: |
SRY-boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000036050 |