| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PDE7A |
| Specificity: |
This antibody reacts specifically with PDE7A |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PDE7A |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
PDE3A, PDE3A and 3B, PDE7B is most highly expressed in pancreas, Phosphodiesterase type 3 isoforms, The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP, alternate splice products of PDE7A, and smooth muscle relaxation, are expressed primarily in cardiovascular tissue and adipose tissue, are highly expressed in skeletal muscle, glycogenolysis, is found in myocardium and platelets and PDE3B is found in lymphocytes, myocardial contractility, respectively, Phosphodiesterases (PDE |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HCP1 |
| Also known as: |
PDE7A Polyclonal Antibody |
| Other name: |
Anti-PDE7A Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PDE7A |
| Short name: |
Anti-PDE7A (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PDE7A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8791 |
| Gene: |
PDE7A |
More about : PDE7A |
| Long gene name: |
phosphodiesterase 7A |
| Locus: |
8q13, 1 |
| Discovery year: |
1994-07-21 |
| GenBank acession: |
L12052 |
| Entrez gene record: |
5150 |
| Pubmed identfication: |
8389765 9521885 |
| Classification: |
Phosphodiesterases |
| Havana BLAST/BLAT: |
OTTHUMG00000164469 |