| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
FOXG1/BF-1 |
| Specificity: |
This antibody reacts specifically with FOXG1/BF-1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human FOXG1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BF-1 is expressed by E8, BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, It may also regulate the response of cerebral cortical progenitors to environmental cues (1), The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1, WH proteins are a family of putative transcriptional regulators with diverse roles in development, also known as foxg1, and are characterized by a highly conserved DNA binding structure, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (1â, such as the cerebral cortex and basal ganglia (1), the WH domain (1, &euro, &ldquo, 4), 5, 5 in telencephalic progenitors (1), 6), 7), The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HFK2 QIN BF1 HFK1 HFK3 HBF-3 |
| Also known as: |
FOXG1/BF-1 Polyclonal Antibody |
| Other name: |
Anti-FOXG1/BF-1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
FOXG1/BF-1 |
| Short name: |
Anti-FOXG1/BF-1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-FOXG1/BF-1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3811 |
| Gene: |
FOXG1 |
More about : FOXG1 |
| Long gene name: |
forkhead box G1 |
| Synonyms gene: |
FKHL2 FOXG1B FKHL4 FKH2 FKHL1 FOXG1C FKHL3 FOXG1A |
| Synonyms gene name: |
forkhead box G1B forkhead box G1C forkhead box G1A |
| Locus: |
14q12 |
| Discovery year: |
1994-12-07 |
| Entrez gene record: |
2290 |
| Pubmed identfication: |
7959731 17260156 |
| Classification: |
Forkhead boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000140187 |