| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SEMA3E/Semaphorin 3E |
| Specificity: |
This antibody reacts specifically with SEMA3E/Semaphorin 3E |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SEMA3E/Semaphorin 3E |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular â, Mutations in the SEMA3E gene are associated with CHARGE syndrome, SEMA3E is a secreted semaphorin with 775 amino acids, Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain, a disorder characterized by cranial nerve dysfunction, and growth retardation, blocks of conserved sequences and no obvious repeats, cardiac anomalies, choanal atresia, coloboma of the eye, genitourinary abnormalities, guiding the development of intricate networks of neural tissue, inner and external ear abnormalities, &euro, &euro, &oelig, Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans, semaphorinâ, domain of approximately 500 amino acids containing 14-16 cysteines |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
M-SemaK KIAA0331 coll-5 |
| Also known as: |
SEMA3E/Semaphorin 3E Polyclonal Antibody |
| Other name: |
Anti-SEMA3E/Semaphorin 3E Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SEMA3E/Semaphorin 3E |
| Short name: |
Anti-SEMA3E/Semaphorin 3E (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
(semaphorin) 3E/Semaphorin 3E (polyclonal), ALEXA Fluor 594, immunoglobulin domain (Ig), secreted, short basic domain, antibody to-sema domain |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
(semaphorin) 3E, Extracellular, SEMA3E and IDBG-24532 and ENSG00000170381 and 9723, SEMA3E and IDBG-631012 and ENSBTAG00000014920 and 535644, Sema3e and IDBG-135740 and ENSMUSG00000063531 and 20349, coll-5 and M-SEMAH and M-SemaK and SEMAH, immunoglobulin domain (Ig), secreted, semaphorin receptor binding, short basic domain, this GO :0001569 and patterning of blood vessels and biological process this GO :0001953 and negative regulation of cell-matrix adhesion and biological process this GO :0002040 and sprouting angiogenesis and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007411 and axon guidance and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0016020 and membrane and cellular component this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0030215 and semaphorin receptor binding and molecular function this GO :0050808 and synapse organization and biological process this GO :0071526 and semaphorin-plexin signaling pathway and biological process this GO :2000249 and regulation of actin cytoskeleton reorganization and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0030215 : semaphorin receptor binding, this GO :0005515 : protein binding, this GO :0030215 : semaphorin receptor binding, sema domain |
| Identity: |
10727 |
| Gene: |
SEMA3E |
More about : SEMA3E |
| Long gene name: |
semaphorin 3E |
| Synonyms gene: |
SEMAH |
| Synonyms gene name: |
(semaphorin) 3E , immunoglobulin domain (Ig), secreted, sema domain, short basic domain |
| Synonyms name: |
M-sema H |
| Locus: |
7q21, 11 |
| Discovery year: |
1999-06-25 |
| GenBank acession: |
AB002329 |
| Entrez gene record: |
9723 |
| Pubmed identfication: |
9205841 9515811 |
| RefSeq identity: |
NM_012431 |
| Classification: |
Semaphorins Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000154693 |