| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Nocturnin |
| Specificity: |
This antibody reacts specifically with Nocturnin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Nocturnin |
| Gene ID: |
25819 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In Xenopus retinal photoreceptor cells, Mice lacking Nocturnin remain lean on high fat diets with a reduction in visceral fat, Nocturnin is thought to be responisble for turning off genes that are involved in circadian regulation, Nocturnin plays a role in circadian regulation as well as diet-induced obesity, The mRNA abundance of Nocturnin exhibits circadian rhythmicity, heart, kidney and liver, kidney and testis, peaking after dusk in photoreceptors, spleen, the rhythmic regulation of Nocturnin is thought to be controlled by phosphorylated CREB, which suggests that this protein may also be responsible for lipid metabolism and fat storage, Nocturnin is a 431 amino acid circadian deadenylase protein that is expressed in a broad range of tissues with greatest abundance in the liver |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CCR4L Ccr4c NOC |
| Also known as: |
Nocturnin Polyclonal Antibody |
| Other name: |
Anti-Nocturnin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Nocturnin |
| Short name: |
Anti-Nocturnin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Nocturnin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14254 |
| Gene: |
NOCT |
More about : NOCT |
| Long gene name: |
nocturnin |
| Synonyms gene: |
CCRN4L |
| Synonyms gene name: |
CCR4-like (carbon catabolite repression 4, S, cerevisiae) , cerevisiae) CCR4 carbon catabolite repression 4-like (S |
| Locus: |
4q31, 1 |
| Discovery year: |
2000-12-14 |
| GenBank acession: |
AF183961 |
| Entrez gene record: |
25819 |
| Pubmed identfication: |
10521507 11394964 |
| RefSeq identity: |
NM_012118 |
| Havana BLAST/BLAT: |
OTTHUMG00000161271 |