| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Synaptojanin 2 |
| Specificity: |
This antibody reacts specifically with Synaptojanin 2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Synaptojanin 2 |
| Gene ID: |
8871 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Eight splice variants of synaptojanin 2 have been detected, Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues, Synaptojanins are characterized by an N-terminal SAC1-like sequence, Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton, Synaptojanins exist as two isoforms, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4, and each isoform has multiple variants produced by alternative splicing, including a brain specific isoform, synaptojanin 1 and 2, which differ in the C-terminal domain, which generate second messengers in response to extracellular signals, 5-bisphosphate as a substrate, The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
INPP 5H, INPP5H, Inositol phosphate 5' phosphatase 2, KIAA0348, MGC44422, SJ2, SYNJ 2, SYNJ2_HUMAN, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 2, Synaptic inositol-1, Synaptojanin-2, Synaptojanin2, Synj2, 5-trisphosphate 5-phosphatase 2 |
| Also known as: |
Synaptojanin 2 Antibody |
| Other name: |
Anti-Synaptojanin 2 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Synaptojanin 2 |
| Short name: |
Fluor 594, Anti-Synaptojanin 2 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Synaptojanin 2 |