| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RFC1 |
| Specificity: |
This antibody reacts specifically with RFC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RFC1 |
| Gene ID: |
5981 |
| Swiss Prot: |
P35251 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, Binds the PO-B transcription element as well as other GA rich DNA sequences, Can bind single- or double-stranded DNA, Could play a role in DNA transcription regulation as well as DNA replication and/or repair, Interacts with C-terminus of PCNA, This subunit binds to the primer-template junction, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair, The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FOLT RFC1 |
| Also known as: |
RFC1 Polyclonal Antibody |
| Other name: |
Anti-RFC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RFC1 |
| Short name: |
Anti-RFC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RFC1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
10937 |
| Gene: |
SLC19A1 |
More about : SLC19A1 |
| Long gene name: |
solute carrier family 19 member 1 |
| Synonyms gene name: |
member 1 , solute carrier family 19 (folate transporter) |
| Synonyms name: |
reduced folate carrier 1 Folate transporter 1 |
| Locus: |
21q22, 3 |
| Discovery year: |
1995-05-01 |
| GenBank acession: |
U15939 |
| Entrez gene record: |
6573 |
| Pubmed identfication: |
9570943 |
| Classification: |
Solute carriers Minor histocompatibility antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000090397 |