| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HOXA3 |
| Specificity: |
This antibody reacts specifically with HOXA3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HOXA3 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
HOX genes that occupy the same relative position along the 5â, HoxA3, HoxA3 also regulates hindbrain development by controlling the axon projection pattern of motor neurons and sensory neurons of the proximal and distal ganglia, Its expression in the third pharyngeal arch and pouch is required for development of the third arch artery, Specifically, The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, and carotid body, and homozygous null HoxA3 mutants lack the carotid body, coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome, in conjunction with Pax1, mediates the development of the thymus, parathyroid gland, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis, to 3â, which are dispersed over four chromosomes, &euro, &euro, &trade, &trade, The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
HOXA3 Polyclonal Antibody |
| Other name: |
Anti-HOXA3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HOXA3 |
| Short name: |
Anti-HOXA3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-homeobox A3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0010159 and specification of organ position and biological process this GO :0021615 and glossopharyngeal nerve morphogenesis and biological process this GO :0030878 and thyroid gland development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0048538 and thymus development and biological process this GO :0048645 and organ formation and biological process this GO :0048704 and embryonic skeletal system morphogenesis and biological process this GO :0048706 and embryonic skeletal system development and biological process this GO :0051216 and cartilage development and biological process this GO :0060017 and parathyroid gland development and biological process this GO :0071837 and HMG box domain binding and molecular function, HMG box domain binding, HOX1 and HOX1E, HOXA3 and IDBG-10346 and ENSG00000105997 and 3200, HOXA3 and IDBG-633595 and ENSBTAG00000008139 and 509991, Hoxa3 and IDBG-251785 and ENSMUSG00000079560 and 15400, nuclei, this GO :0001525 and angiogenesis and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0071837 : HMG box domain binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0043565 : sequence-specific DNA binding, this GO :0071837 : HMG box domain binding, homeobox A3 |
| Identity: |
5104 |
| Gene: |
HOXA3 |
More about : HOXA3 |
| Long gene name: |
homeobox A3 |
| Synonyms gene: |
HOX1E HOX1 |
| Synonyms gene name: |
homeo box A3 |
| Locus: |
7p15, 2 |
| Discovery year: |
1990-06-15 |
| Entrez gene record: |
3200 |
| Pubmed identfication: |
1973146 1358459 |
| Classification: |
HOXL subclass homeoboxes |
| Havana BLAST/BLAT: |
OTTHUMG00000023209 |