| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CACNA1F |
| Specificity: |
This antibody reacts specifically with CACNA1F |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CACNA1F |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
L-type Ca2+ currents initiate muscle contraction, L-type calcium channels may form macromolecular signaling complexes with G protein-coupled receptors, N-, P-, Q-, T-, and R- types, and can be regulated through second-messenger activated protein phosphorylation pathways, and gene transcription, and they are involved in a variety of Ca2+-dependent processes, endocrine secretion, hormone or neurotransmitter release and gene expression, including muscle contraction, thereby enhancing the selectivity of regulating specific targets, Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Cav1, 4 JM8 JMC8 CSNBX2 CORDX3 CSNB2A OA2 |
| Also known as: |
CACNA1F Polyclonal Antibody |
| Other name: |
Anti-CACNA1F Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CACNA1F |
| Short name: |
Anti-CACNA1F (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CACNA1F (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1393 |
| Gene: |
CACNA1F |
More about : CACNA1F |
| Long gene name: |
calcium voltage-gated channel subunit alpha1 F |
| Synonyms gene: |
CSNB2 AIED |
| Synonyms gene name: |
Aland island eye disease (Forsius-Eriksson ocular albinism, L type, alpha 1F subunit , ocular albinism type 2) calcium channel, voltage-dependent |
| Locus: |
Xp11, 23 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
AA019975 |
| Entrez gene record: |
778 |
| Pubmed identfication: |
9344658 9662400 16382099 12111638 17525176 |
| RefSeq identity: |
NM_005183 |
| Classification: |
Calcium voltage-gated channel subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000022703 |
| Locus Specific Databases: |
Mutations of the L-type Calcium-Channel Gene Mental Retardation database |