| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TMPRSS5 |
| Specificity: |
This antibody reacts specifically with TMPRSS5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TMPRSS5 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A member of the peptidase S1 family, Defects in the gene encoding TMPRSS5 are associated with deafness, TMPRSS5 (transmembrane protease, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, allow desquamation of tumor cells into the surrounding environment, also known as spinesin, and is encoded by a gene that maps to human chromosome 11q23, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors, serine 5), 2, Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC141886 MGC148044 |
| Also known as: |
TMPRSS5 Polyclonal Antibody |
| Other name: |
Anti-TMPRSS5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TMPRSS5 |
| Short name: |
Anti-TMPRSS5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-TMPRSS5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14908 |
| Gene: |
TMPRSS5 |
More about : TMPRSS5 |
| Long gene name: |
serine 5 , transmembrane protease |
| Synonyms name: |
spinesin |
| Locus: |
11q23, 2 |
| Discovery year: |
2001-04-05 |
| GenBank acession: |
AB028140 |
| Entrez gene record: |
80975 |
| RefSeq identity: |
NM_030770 |
| Classification: |
Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000168186 |