| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NARF |
| Specificity: |
This antibody reacts specifically with NARF |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NARF |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, Expressed ubiquitously with highest expression in heart, NARF (nuclear prelamin A recognition factor), NARF binds to the C-terminal end of prenylated prelamin A and may be a member of a prelamin A-containing endoprotease complex, NARF is expressed as three isoforms due to alternative splicing events and, NARF may be involved in heterochromatin organization, also known as IOP2, both of which are important for a variety of functions, including membrane attachment, is a 456 amino acid nuclear protein that belongs to the NARF family, may be phosphorylated by ATM or ATR, protein-protein interactions and signaling events, skeletal muscle and brain, upon DNA damage, via its association with prelamin A, Prenylation and methylation are two forms of protein modification |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
STRIN NARF |
| Also known as: |
NARF Polyclonal Antibody |
| Other name: |
Anti-NARF Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NARF |
| Short name: |
Anti-NARF (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NARF (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17765 |
| Gene: |
RNF138 |
More about : RNF138 |
| Long gene name: |
ring finger protein 138 |
| Synonyms gene name: |
E3 ubiquitin protein ligase , ring finger protein 138 |
| Synonyms name: |
nemo-like kinase associated ring finger protein |
| Locus: |
18q12, 1 |
| Discovery year: |
2003-05-21 |
| GenBank acession: |
AF162680 |
| Entrez gene record: |
51444 |
| Pubmed identfication: |
22155992 16714285 |
| RefSeq identity: |
NM_016271 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000132265 |