| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PCDHGB1 |
| Specificity: |
This antibody reacts specifically with PCDHGB1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PCDHGB1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
As a member of the gamma subfamily B, B and C), PCDHGB1 (Protocadherin gamma B1) is a 927 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster, PCDHGB1 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system, The protocadherein gamma cluster consists of three subfamilies (A, There are three protocadherin gene clusters designated alpha, There are two isoforms of PCDHGB1 that are produced as a result of alternative splicing events, Typical of gamma protocadherins, With localization to synapses, all of which contain multiple tandemly arranged genes, beta and gamma, members of the gamma cluster of protocadherins are essential for neuronal survival, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PCDH-GAMMA-B1 |
| Also known as: |
PCDHGB1 Polyclonal Antibody |
| Other name: |
Anti-PCDHGB1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PCDHGB1 |
| Short name: |
Anti-PCDHGB1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
1 (polyclonal), ALEXA Fluor 594, antibody to-protocadherin g subfamily B |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
1, PCDHGB1 and IDBG-408879 and ENSG00000254221 and 56104, PCDHGB2 and IDBG-646107 and ENSBTAG00000037968 and 100848197, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding, protocadherin gamma subfamily B |
| Identity: |
8708 |
| Gene: |
PCDHGB1 |
More about : PCDHGB1 |
| Long gene name: |
1 , protocadherin gamma subfamily B |
| Synonyms name: |
1, isoform 2 , protocadherin gamma subfamily B |
| Locus: |
5q31 |
| Discovery year: |
2000-06-28 |
| GenBank acession: |
AF152517 |
| Entrez gene record: |
56104 |
| Pubmed identfication: |
10380929 |
| RefSeq identity: |
NM_018922 |
| Classification: |
Clustered protocadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000163681 |