| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MYBPC1 |
| Specificity: |
This antibody reacts specifically with MYBPC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MYBPC1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Additionally, Chromosome 12 is associated with a variety of diseases and afflictions, Existing as a member of the immunoglobulin superfamily, Kniest dysplasia, MYBPC1 functions as a thick filament-associated protein that localizes to striated muscle bands in vertebrae and is thought to modify the activity of select ATPases, MYBPC1 may play a role in the modulation of muscle contraction and in the overall structural integrity of the cell, Noonan syndrome and Trisomy 12p, The gene encoding MYBPC1 maps to human chromosome 12, achondrogenesis, including hypochondrogenesis, which causes facial developmental defects and seizure disorders, which encodes over 1, 100 genes and comprises approximately 4, 141 amino acid protein that contains three fibronectin type-III domains and seven Ig-like C2-type domains, 5% of the human genome, MYBPC1 is a 1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
MYBPC1 Polyclonal Antibody |
| Other name: |
Anti-MYBPC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MYBPC1 |
| Short name: |
Anti-MYBPC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, slow classification (polyclonal), antibody to-myosin binding protein C |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, LCCS4 and MYBPCC and MYBPCS, MYBPC1 and IDBG-53185 and ENSG00000196091 and 4604, MYBPC1 and IDBG-637065 and ENSBTAG00000011392 and 510763, Mybpc1 and IDBG-183668 and ENSMUSG00000020061 and 109272, slow type, this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006936 and muscle contraction and biological process this GO :0007155 and cell adhesion and biological process this GO :0008307 and structural constituent of muscle and molecular function this GO :0030016 and myofibril and cellular component this GO :0030049 and muscle filament sliding and biological process this GO :0031432 and titin binding and molecular function this GO :0032982 and myosin filament and cellular component, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0005515 : protein binding and also this GO :0008307 : structural constituent of muscle and also this GO :0031432 : titin binding, this GO :0005515 : protein binding, this GO :0008307 : structural constituent of muscle, this GO :0031432 : titin binding, titin binding, myosin binding protein C |
| Identity: |
7549 |
| Gene: |
MYBPC1 |
More about : MYBPC1 |
| Long gene name: |
myosin binding protein C, slow type |
| Synonyms gene name: |
myosin-binding protein C, slow-type |
| Locus: |
12q23, 2 |
| Discovery year: |
1993-12-15 |
| Entrez gene record: |
4604 |
| Pubmed identfication: |
8375400 16918501 |
| Classification: |
I-set domain containing Myosin binding proteins Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000170274 |