| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
K5A/NKHC1 |
| Specificity: |
Contains 1 kinesin-motor domain, Kinesin subfamily, Belongs to the kinesin-like protein family, KIF5A/NKHC1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human KIF5A/NKHC1 |
| Gene ID: |
3798 |
| Swiss Prot: |
Q12840 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Kinesin superfamily proteins like NKHC1 are the molecular motors conveying cargos along microtubules, Mutations in the gene encoding NKHC1 cause autosomal dominant spastic paraplegia 10, NKHC1 has a pan-neuronal distribution in the nervous system, NKHC1 is concentrated in the perinuclear region of the cell body, NKHC1 is distributed throughout the central nervous system and is enriched in subsets of neurons, Rat tissue extracts by immunoblot of NKHC1 can produce a doublet only in brain and sciatic nerve tissue, Within cultured hippocampal neurons, &euro, &euro, &oelig, NKHC1 is a neuronal-specific component of a multi-subunit â, molecular motorâ, complex that mediates intracellular organelle transport |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D12S1889 NKHC MY050 |
| Also known as: |
KIF5A/NKHC1 Polyclonal Antibody |
| Other name: |
Anti-KIF5A/NKHC1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
KIF5A/NKHC1 |
| Short name: |
Anti-KIF5A/NKHC1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-KIF5A/NKHC1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6323 |
| Gene: |
KIF5A |
More about : KIF5A |
| Long gene name: |
kinesin family member 5A |
| Synonyms gene: |
SPG10 |
| Synonyms gene name: |
spastic paraplegia 10 (autosomal dominant) |
| Locus: |
12q13, 3 |
| Discovery year: |
1998-08-24 |
| GenBank acession: |
U06698 |
| Entrez gene record: |
3798 |
| Pubmed identfication: |
9858832 10441583 16489470 |
| RefSeq identity: |
NM_004984 |
| Classification: |
Kinesins |
| Havana BLAST/BLAT: |
OTTHUMG00000170143 |