| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TNFRSF25 |
| Specificity: |
This antibody reacts specifically with TNFRSF25 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human TNFRSF25 |
| Gene ID: |
8718 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Jul 2008], Knockout studies in micesuggested the role of this gene in the removal of self-reactive Tcells in the thymus, Multiple alternatively spliced transcriptvariants of this gene encoding distinct isoforms have beenreported, Thealternative splicing of this gene in B and T cells encounters aprogrammed change upon T-cell activation, Thesignal transduction of this receptor is mediated by various deathdomain containing adaptor proteins, This receptor has been shown tostimulate NF-kappa B activity and regulate cell apoptosis, This receptor is expressed preferentiallyin the tissues enriched in lymphocytes, [provided by RefSeq, and is thought to beinvolved in controlling lymphocyte proliferation induced by T-cellactivation, and it may play a role inregulating lymphocyte homeostasis, membrane bound isoforms, most of which are potentially secreted molecules, which predominantlyproduces full-length, The protein encoded by this gene is a member of theTNF-receptor superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DR3 TRAMP WSL-1 LARD WSL-LR DDR3 TR3 APO-3 |
| Also known as: |
TNFRSF25 Polyclonal Antibody |
| Other name: |
Anti-TNFRSF25 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TNFRSF25 |
| Short name: |
Anti-TNFRSF25 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 25 (polyclonal), antibody to-tumor necrosis factor receptor superfamily |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
APO-3 and DDR3 and DR3 and LARD and TNFRSF12 and TR3 and TRAMP and WSL-1 and WSL-LR, BT, Extracellular, TNFRSF25 and IDBG-227097 and ENSG00000215788 and 8718, Tnfrsf25 and IDBG-206339 and ENSMUSG00000024793 and 85030, member 25, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005031 and tumor necrosis factor-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005031 : tumor necrosis factor-activated receptor activity and also this GO :0005515 : protein binding, this GO :0005031 : tumor necrosis factor-activated receptor activity, this GO :0005515 : protein binding, 30010 and IDBG-633838 and ENSBTAG00000006519 and 783432, tumor necrosis factor receptor superfamily |
| Identity: |
11910 |
| Gene: |
TNFRSF25 |
More about : TNFRSF25 |
| Long gene name: |
TNF receptor superfamily member 25 |
| Synonyms gene: |
TNFRSF12 |
| Synonyms gene name: |
member 12 (translocating chain-association membrane protein) tumor necrosis factor receptor superfamily, member 25 , tumor necrosis factor receptor superfamily |
| Locus: |
1p36, 31 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
U72763 |
| Entrez gene record: |
8718 |
| Pubmed identfication: |
9052839 8934525 |
| RefSeq identity: |
NM_148965 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000000831 |