| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ADRA1B |
| Specificity: |
This antibody reacts specifically with ADRA1B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ADRA1B |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
-1B and -1D, Jul 2008], There are 3 alpha-1-AR subtypes: alpha-1A, They activate mitogenic responses and regulate growth and proliferation of many cells, This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region, This gene encodes alpha-1B-adrenergic receptor, Thus, [provided by RefSeq, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation, this normal cellular gene is identified as a protooncogene, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines, Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
ADRA1B Polyclonal Antibody |
| Other name: |
Anti-ADRA1B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ADRA1B |
| Short name: |
Anti-ADRA1B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-adrenoceptor a 1B (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ADRA1 and ALPHA1BAR, ADRA1B and IDBG-55923 and ENSG00000170214 and 147, Adra1b and IDBG-164464 and ENSMUSG00000050541 and 11548, BT, nuclei, protein heterodimerization activity, this GO :0001974 and blood vessel remodeling and biological process this GO :0001975 and response to amphetamine and biological process this GO :0001987 and vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure and biological process this GO :0001996 and positive regulation of heart rate by epinephrine-norepinephrine and biological process this GO :0001997 and positive regulation of the force of heart contraction by epinephrine-norepinephrine and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004937 and alpha1-adrenergic receptor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007512 and adult heart development and biological process this GO :0007626 and locomotory behavior and biological process this GO :0008283 and cell proliferation and biological process this GO :0008542 and visual learning and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016049 and cell growth and biological process this GO :0019229 and regulation of vasoconstriction and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0035265 and organ growth and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043278 and response to morphine and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045818 and negative regulation of glycogen catabolic process and biological process this GO :0045819 and positive regulation of glycogen catabolic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048148 and behavioral response to cocaine and biological process this GO :0055117 and regulation of cardiac muscle contraction and biological process this GO :0071875 and adrenergic receptor signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004937 : alpha1-adrenergic receptor activity and also this GO :0046982 : protein heterodimerization activity, this GO :0004937 : alpha1-adrenergic receptor activity, this GO :0046982 : protein heterodimerization activity, 27996 and IDBG-646421 and ENSBTAG00000040253 and 407140, adrenoceptor alpha 1B |
| Identity: |
278 |
| Gene: |
ADRA1B |
More about : ADRA1B |
| Long gene name: |
adrenoceptor alpha 1B |
| Synonyms gene name: |
adrenergic, alpha-1B-, receptor |
| Locus: |
5q33, 3 |
| Discovery year: |
1991-06-04 |
| GenBank acession: |
L31773 |
| Entrez gene record: |
147 |
| Classification: |
Adrenoceptors |
| Havana BLAST/BLAT: |
OTTHUMG00000130327 |