| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SLC4A4 |
| Specificity: |
This antibody reacts specifically with SLC4A4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SLC4A4 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH, Multiple transcript variants encoding different isoforms have been found for this gene, Mutations in this gene are associated with proximal renal tubular acidosis, Oct 2008], SLC4A4 interacts with carbonic anhydrase 2 and carbonic anhydrase 4 which may regulate transporter activity, There are four named isoforms produced by alternative splicing, [provided by RefSeq, SLC4A4 (Electrogenic sodium bicarbonate cotransporter 1) is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3, This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NBC1 HNBC1 NBC2 pNBC hhNMC |
| Also known as: |
SLC4A4 Polyclonal Antibody |
| Other name: |
Anti-SLC4A4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SLC4A4 |
| Short name: |
Anti-SLC4A4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SLC4A4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11030 |
| Gene: |
SLC4A4 |
More about : SLC4A4 |
| Long gene name: |
solute carrier family 4 member 4 |
| Synonyms gene: |
SLC4A5 |
| Synonyms gene name: |
member 4 , member 4 solute carrier family 4 (sodium bicarbonate cotransporter), sodium bicarbonate cotransporter, solute carrier family 4 |
| Locus: |
4q13, 3 |
| Discovery year: |
1998-12-11 |
| GenBank acession: |
AF007216 |
| Entrez gene record: |
8671 |
| Pubmed identfication: |
9235899 9651366 |
| RefSeq identity: |
NM_003759 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000129907 |