| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MPL |
| Specificity: |
This antibody reacts specifically with MPL |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Helical |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MPL |
| Gene ID: |
4352 |
| Swiss Prot: |
P40238 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
May represent a regulatory molecule specific for TPO-R-dependent immune responses, Receptor for thrombopoietin |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD110 TPOR |
| Also known as: |
MPL Polyclonal Antibody |
| Other name: |
Anti-MPL Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MPL |
| Short name: |
Anti-MPL (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-myeloproliferative leukemia virus oncogene (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, C-MPL and CD110 and MPLV and THCYT2 and TPOR, MPL and IDBG-97403 and ENSG00000117400 and 4352, Mpl and IDBG-181592 and ENSMUSG00000006389 and 17480, Plasma membranes, protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004896 and cytokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030168 and platelet activation and biological process this GO :0032642 and regulation of chemokine production and biological process this GO :0048872 and homeostasis of number of cells and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004896 : cytokine receptor activity and also this GO :0005515 : protein binding, this GO :0004896 : cytokine receptor activity, this GO :0005515 : protein binding, 26255 and IDBG-640482 and ENSBTAG00000003781 and 528492, myeloproliferative leukemia virus oncogene |
| Identity: |
7217 |
| Gene: |
MPL |
More about : MPL |
| Long gene name: |
MPL proto-oncogene, thrombopoietin receptor |
| Synonyms gene name: |
myeloproliferative leukemia virus oncogene |
| Locus: |
1p34, 2 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
M90102 |
| Entrez gene record: |
4352 |
| Pubmed identfication: |
1608974 |
| RefSeq identity: |
NM_005373 |
| Classification: |
CD molecules Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000007429 |
| Locus Specific Databases: |
LRG_510 |