| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CD86 |
| Specificity: |
This antibody reacts specifically with CD86 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Intracellular, Membrane bound |
| Antigen Source: |
KLH conjugated synthetic peptide derived from rat CD86 |
| Gene ID: |
56822 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing results in several transcript variants encoding different isoforms, Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell, Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4, May 2011], This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily, [provided by RefSeq |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
B7, 2 B7-2 |
| Also known as: |
CD86 Polyclonal Antibody |
| Other name: |
Anti-CD86 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CD86 |
| Short name: |
Anti-CD86 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CD86 molecule (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
B7-2 and B7, CD86 and IDBG-52336 and ENSG00000114013 and 942, CD86 and IDBG-633264 and ENSBTAG00000013118 and 414345, Cd86 and IDBG-158071 and ENSMUSG00000022901 and 12524, Cell surfaces, DNA-templated and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051607 and defense response to virus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071248 and cellular response to metal ion and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process, coreceptor activity, this GO :0001878 and response to yeast and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002309 and T cell proliferation involved in immune response and biological process this GO :0002668 and negative regulation of T cell anergy and biological process this GO :0004872 and receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007568 and aging and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034341 and response to interferon-gamma and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042113 and B cell activation and biological process this GO :0042493 and response to drug and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043017 and positive regulation of lymphotoxin A biosynthetic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045404 and positive regulation of interleukin-4 biosynthetic process and biological process this GO :0045630 and positive regulation of T-helper 2 cell differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0015026 : coreceptor activity, 2 and B70 and CD28LG2 and LAB72, CD86 molecule |
| Identity: |
1705 |
| Gene: |
CD86 |
More about : CD86 |
| Long gene name: |
CD86 molecule |
| Synonyms gene: |
CD28LG2 |
| Synonyms gene name: |
B7-2 antigen) , CD86 antigen (CD28 antigen ligand 2 |
| Synonyms name: |
B-lymphocyte antigen B7-2 |
| Locus: |
3q13, 33 |
| Discovery year: |
1994-12-07 |
| Entrez gene record: |
942 |
| Pubmed identfication: |
7513726 |
| RefSeq identity: |
NM_006889 |
| Classification: |
Immunoglobulin like domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000159482 |