| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Pokemon/ZBTB7 |
| Specificity: |
This antibody reacts specifically with Pokemon/ZBTB7 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Pokemon |
| Gene ID: |
51341 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, Electrophoretic mobility shift assays suggested that the NEG-U, Moreover, Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro, Taken together, To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, Transient analysis revealed that the Pokemon promoter is constitutive, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy, but also plays an important role in cell tumorigenesis, its 5'-upstream region was cloned and analyzed, not only regulates the expression of many genes, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate, the POK erythroid myeloid ontogenic factor, whereas the POS-D element was mainly responsible for its strong activity, Pokemon |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FBI-1 LRF DKFZp547O146 pokemon ZNF857A |
| Also known as: |
Pokemon/ZBTB7 Polyclonal Antibody |
| Other name: |
Anti-Pokemon/ZBTB7 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Pokemon/ZBTB7 |
| Short name: |
Anti-Pokemon/ZBTB7 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Pokemon/ZBTB7 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
18078 |
| Gene: |
ZBTB7A |
More about : ZBTB7A |
| Long gene name: |
zinc finger and BTB domain containing 7A |
| Synonyms gene: |
ZBTB7 |
| Synonyms gene name: |
zinc finger and BTB domain containing 7 |
| Synonyms name: |
HIV-1 inducer of short transcripts binding protein lymphoma related factor , zinc finger and BTB domain containing 7A |
| Locus: |
19p13, 3 |
| Discovery year: |
2004-01-16 |
| GenBank acession: |
AF000561 |
| Entrez gene record: |
51341 |
| Pubmed identfication: |
9973611 9927193 |
| RefSeq identity: |
NM_015898 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000181792 |